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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f40679a9adbac868fc129faa353e0905dbfbdfb370e4e253b390970e38644ee' 
  AND token = 'L1dICTZ1jx9yYA7vA34Fj69JQqvHDe0Jzmos+Iemg0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}