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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee51aca51d1c0f52cd7cbb011158106ab7fe1e6899bbedf9a925b378580b4f74' 
  AND token = 'p49ctjhaXpVVaZM82lW3foFX2Hw3H2UvAxfu0t7JWI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}