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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd440fbaac37a481405854a3c5546c8e80e1765747aec4c787f10bbbe7ed38c53' 
  AND token = 'PCCsNpioYZ5/a7qDiFMDiLccaecaBx8n7kpPqOwZpZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}