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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a416471c7f8139b7fa6555e58be13f6ac40a9bab1a71690e2045cb72ecc7fef0' 
  AND token = 'aKK+aaBiWcKaOdhBUHzFdnZPlfOPxO8Pq8AkEozzEqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}