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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21ba66cce76e89baa1394c6e457c4632886518d8904fd5de53843464d1317647' 
  AND token = 'e55+uDjFGHOfhYb1G5d26zi66W43sgnJGP3eRbyGF78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}