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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3afc7c548dca8795fdc579be7003c7d6f366a0cb4222489133a1f2308510e344' 
  AND token = 'zjtlQ0694Bs6LcOi0vuxc4bXKPNl2Nm1X0ng2fIOoz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}