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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '131b033ce63fa0b5f253926911cc7cc2f90f1bc8f829408c4cb2cee82e92096f' 
  AND token = 'Rz2WWbD/v/xsGUb9Y1zZvEmr/ve9hvDUwyN4UYhca2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}