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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad05af530353e82db58eccddcba2a23f377d923fb4bd8b73b9363bb262225500' 
  AND token = 'r5citIJ1f1wOstCfWmFTX4azc0XUqqTT7SAgVwu81AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}