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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0c00613a7d464c0040bad8238a49e94e407f5e91e95e7fed405fcdfac67d55' 
  AND token = 'sJTwgAtgYlRXpkxNeu2CESVO996Fv9qEQgsDgyoql6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}