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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14581fffd97654f10782d61e06f76bda5e86caa8d04e95a1ae9d8460aaf3385b' 
  AND token = 'kMAeKvezRWmTwUpR+2aexls9BqAzegDuDOBg1IbGWGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}