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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3abc9e5fb990ba33cadf47850e1be668a2b7dc4a88fc7b2d1006a54c64fb30' 
  AND token = '+x2Y0QDwHzFT+3HhMIWz3vCx14dDSJmue2pFq5Vfauc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}