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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d40d730e2f9e54a6ebfdca7c47b72078dcdb4b0ba5883c8ac61766fc31ebeac' 
  AND token = 'KehVhIusFO/iEWjOzO3IU/tN+kkmF/FrjQ6HTeWLdd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}