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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca40e5bdf1af245a99922b233e2f78d1d3225b1f1d2abfe61521b5a43d353c96' 
  AND token = 'aGcrlkZpvjby3DnS1eyHKS+B7V6nFpuqqTwSDM6aSY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}