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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c850ea23b26a88432f50077ba7a03d1960c96f602b9b4e8861ebc75ffbec103d' 
  AND token = 'T6WfFBqpY3c9VZSY9MMgmfCbNwC4WV9JWZr49bve8E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}