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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff7a4aeeb6cd211a704212eb37bb001b3e806d0211042912576d1738fa3227b' 
  AND token = 'SH9wKQ/3kGvEZETru/D5gdMpMmx5Tr0BVpavaeHlrjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}