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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa3f64cccad57110dceaf414be91b3d2a83917ebd4f6804b1f2cfbc6628cd321' 
  AND token = 'XT2fcCtsagZaVAvrx0Px/8YKac3HYbb1NAOo+7KFCK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}