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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b57d1726e679108e7ae679cfd2e4cd29f8440aab47c5700f88211b69db9ce2ba' 
  AND token = 'v9Q5ZOHsVm0C+Vgiw3DNNZ84hargzSOcFNygjMZ49WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}