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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5151e012e422702405f9929c0d1d7a44b0db5f5641b09c11b36c49202133c4d' 
  AND token = 'Z3oBodHnE3d6V67E1464DF+jz/r7xZ90hpzXVRWJNVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}