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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fa1b424d76f05413fdfe5f7a4b9b7993fc2b047a76fbb9df878e6d938730cf' 
  AND token = 'OapFa3ZZM++sQR4binAcLj45ZwRm/zdG+8rE5MDtP+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}