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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7adcd19bef21aec22bbc399e7a2f4b8821643b2d75f70c4b03078cb3ab2e556e' 
  AND token = 'POqaStIK3o400SL/RTOBQngrC4gflcXgCz5afy7E/MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}