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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3022d3911e97c8a91d3ac7b027fa57f23e1ac3450239bf3067bab345629ad26' 
  AND token = 'Dc2JNVSaIdloIYvcXzkn1xXMQKqA3Q/mhj4J5r0Soqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}