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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456452f20f1bf27a1e7aa2d5a5a8cf9c603fb2f0496ba65264d9ed71d13d6c76' 
  AND token = 'XljgVaJL2qWLzc3G+kIY0y1DUYOS/GOy4fQY4VM4rqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}