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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0df59b198ca17ca608420ab2c2c849b53edd2dc1f0b3e269eb44052d5aca37' 
  AND token = 'tmTmenYM3IJrXxxujlC9X8LoR33ieGH7/775NaiQA3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}