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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f100cb21f76c16433f2869843be55b3bc809d7377e55b6daf44588c54a29cf3' 
  AND token = 'NYb2vG+7YAplhR5v0jHouXvL3AT5g7F8NvgnERT66vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}