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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3911ebbab75c535b4888de2ae46703e18ed2e54a6f87d1d84ba14a7d9a1b57' 
  AND token = 'jENEIKGWtdheM+tCw6Wd8zkSyyCPs14wpx802VVDSdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}