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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27feb6e0b03c78266238918b335ee0248bc22d3eb02ce7be2e8729e9226f8916' 
  AND token = 'cuCWPr3aGaTusGaLyYDfWQE2SG8V5i+54Dcx61dJqt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}