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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af18add49813a88d03a7e21a398b7c7b4375eff7f6df8856c6f7cdf1dcd68b6c' 
  AND token = 'ljCo6mwqaqpoetpryyrB4akfPKQLlRm6UOm3JFbnK2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}