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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38100837d5d5d97ba474d037868f358b7c4dbd95b0782924d80b3f2009ce0907' 
  AND token = 'hM6+vCyJmnfAbQZgiDg9R2pMRwU7D/YYuX0etaa3YkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}