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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf540356824a0393a6bc3f7bb34dee7fffe31eb93461ac114d1007c9172abedd' 
  AND token = '2ERDnsqi/V9oAt026/edUYsIzpBviXrD0AiKraNaGXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}