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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e58d0d1be83a7552b83e178fa6da02550c63c028ae5ca422c059781587f860f7' 
  AND token = 'lFn/5KbRHHwddcrTXdT7kr60dPmF3K7++IUZaG0LMW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}