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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d1c5270f2dab0810316cb8d52e768f8e6257ce5425dbc58a952e40b815de70' 
  AND token = 'WzB+eWDwgr2kA8xz9K8lRsYgPTxfQs1VU0rZVJNyoA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}