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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c2b9c429e896460c1950f1008cff940c189849e96e5c0199d3ade03119a8a4' 
  AND token = '/0VuO3LT4eDTQXUySawrPNZemA7WLANcVTgAye4wUa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}