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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00bfc09faaf350fa2d2405d28c42b2393dbd639f0795293d7b8ea349c4bf535e' 
  AND token = 'xPMPPnkpw0E+PX6+vF7iDDpkfgQfnw+dVg4+pZ7kiLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}