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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad3da94744be0995bf8e4e1babfbf25180823d888ff067b82110363a789bdc74' 
  AND token = 'Q48lQMRteWS3SVF+sYbVX4mriBNrt72OtX5X+RPLNPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}