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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0e6acc54531026a3cc18d4c77feb86253e034ef77b543720296658eacd9bea' 
  AND token = 'zbFgNGv/e5M5yNiqEoSH+gnPUKkt7nUyFJHaUx1N5kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}