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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a389aaf881d4a261ba7873c002314741f8bc5bdc751f68a0e1d03778f3212cff' 
  AND token = 'ci7Y9FQxB4eZOwKQnS7ywtKisy56jV4JTu3u4w82rJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}