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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73cbac7c476c8d9456fd49642fb2e8c68f217d7cd84c1973f3802126f94c0e65' 
  AND token = 'TeFwqyZ2cqJVIRhz0ci3DqTI0sN3LZvpckuyD4gcvC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}