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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cf988fde1c0c48d4541828faec664237acfa950ffaf3ed32116eec78118652' 
  AND token = 'hSkxK910yYOlTp1sXuOVng6g2vvk0lVLCvkt1NL4aQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}