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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250200a677545a3604fa2a64bdf1e2381f2a9d8301dd6655b81ac81f6a1aa094' 
  AND token = 'wFO2UZCyMpx/fX8693uzwpdlYh1tf68xSiGra3aFbgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}