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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ccefe3afd3952a7f6ebde0097e0475ca7a3c2da28a78b7b9a3bb6159f671ef' 
  AND token = 'RTBeMQe6oiwDtiqOhTqRmFv2YSkRxDrc+RVzNkD1nek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}