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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4e1cb24c0087115f7573f98e40882df952f467230005b78402074456dae852' 
  AND token = 'vXinwDTX8uZaS92KSqt6u79pDsHAqrGFtZdJqzvp8Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}