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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b50fb03a3e5970655a12d278601e0a7ecc8f2c2bed3870208e0651e1a45936a' 
  AND token = '1eKJZx/6IKkEHvluqETd2wNYeE/WLXEsPHaV56lfBFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}