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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729beb50b1e4ee8f65bc3077910aacb4174b257d338693dca8e0f2ad9efad570' 
  AND token = 'aNjkgVzZ5/VNJ88IbrvF9ABWWs2KnedAaLm8n6KK9zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}