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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c80ac49409f35b604db967595f6dd82ad05d3e7fb2e6050ae0a2a4f38cd50fc' 
  AND token = '4tiaD/946gL2PAlvad4PmA+o7nthWAA+7muKc0g5IjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}