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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd36ea8c23fa48d478149ec7aa0bef07b4125e73ee435fabe72f466951a1a55a3' 
  AND token = 'gDhDLJ33zbfMpDysRS3UnHXMZKjVwRo1WPdY7tHdL7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}