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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '685b3a089efe25b6a9da81100951c3da10be5080bd2a8bc140704103d5ccc5f6' 
  AND token = 'GpZP27QD+lhNUY4AAoHyJzwqNNV7QucJVwXII5bkDxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}