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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e293eb8db5d42d27495248001f09fe4143c779456cf8e8113495e00ba16b006' 
  AND token = 'Fh6rqiJlGK2DX6UYpHyHE0V+bFeYVmIpShUIhSYAEhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}