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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c9034327a10d1a7995bfade82169eb715d1a33fe77c92573c0735c5c72ea7a' 
  AND token = 'reOI7H+oTrz9uAR+zi2Amvg22jmgsTvqquxE7Z6tizs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}