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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0669a82495523ac9107d0460606c9fd5282dd11cba5c690613f848fce8a0a7c0' 
  AND token = '3m3RxJ3+r4H1cV+32Hh8NU/PGS+QhQ4DtP1zJ6EHocE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}