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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10df8cc5e2dbeb84f430e120609f2fcacc752cb14285bc4e001f9abc6f93b1ba' 
  AND token = 'Tdfu44m5a16WFk2kiqerJTW1sITGyR8rr4E5Kes9eQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}